Feed Grade Chlortetracycline

Chlortetracycline is a tetracycline-class antibiotic, also known as "Aureomycin." The related information is summarized as follows:

I. Basic Information

Chemical Formula: C22H23ClN2O8

Molecular Weight: 478.88

CAS Number: 57-62-5

Appearance: Golden or yellow crystalline powder

Storage Conditions: 2-8°C

II. Physical and Chemical Properties

Melting Point: 168-169°C (decomposes)

Density: 1.2833 (rough estimate)

Refractive Index: 1.6000 (estimated)

Solubility: Very slightly soluble in water, soluble in saline solutions; its hydrochloride is slightly soluble in methanol, water, ethanol, and insoluble in acetone, ether, chloroform

Stability: Stable in air, darkens gradually under light

III. Source and Preparation

Chlortetracycline is produced by fermentation of Streptomyces aureofaciens. The fermentation broth is acidified and filtered to obtain a precipitate, which is dissolved in ethanol, then precipitated with acid to obtain crude product. This is further dissolved and crystallized into the hydrochloride form.